Cell marking and estimation of transmembrane potentials

Our group deals with marking of single cells and transmembrane potential estimation in single hepatocytes based on using voltage-sensitive probes. This method can be used in real-time research of different factor influences on cells functional state.


Single cells marked with different dyes (DiO, DiD, Sq and JC-1, respectively):

 

Rat hepatocyte cells marked with RE-doped inorganic nanoparticles:

The lipoprotein complex containing activated hydroxyapatite nanoparticles on a plasma membrane surface of hepatocyte cells of rat.

Hepatocyte cell of rat: a) transmitted light image b) luminescent image of the same cell incubated with modified ReVO₄:Eu³⁺ nanocrystals, that interacting only with membrane of cell nucleus

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